Structural basis for RNA-duplex recognition and unwinding by the DEAD-box helicase Mss116p

Anna L. Mallam, Mark Del Campo, Benjamin Gilman, David J. Sidote and Alan M. Lambowitz ()
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Anna L. Mallam: Institute for Cellular and Molecular Biology, and Section of Molecular Genetics and Microbiology, School of Biological Sciences, University of Texas at Austin
Mark Del Campo: Institute for Cellular and Molecular Biology, and Section of Molecular Genetics and Microbiology, School of Biological Sciences, University of Texas at Austin
Benjamin Gilman: Institute for Cellular and Molecular Biology, and Section of Molecular Genetics and Microbiology, School of Biological Sciences, University of Texas at Austin
David J. Sidote: Institute for Cellular and Molecular Biology, and Section of Molecular Genetics and Microbiology, School of Biological Sciences, University of Texas at Austin
Alan M. Lambowitz: Institute for Cellular and Molecular Biology, and Section of Molecular Genetics and Microbiology, School of Biological Sciences, University of Texas at Austin

Nature, 2012, vol. 490, issue 7418, 121-125

Abstract: Analysis of the yeast DEAD-box nucleic acid helicase Mss116p provides a structural model for how DEAD-box proteins recognize and unwind RNA duplexes.

Date: 2012
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DOI: 10.1038/nature11402

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