Targeting VEGF-B as a novel treatment for insulin resistance and type 2 diabetes

Carolina E. Hagberg, Annika Mehlem, Annelie Falkevall, Lars Muhl, Barbara C. Fam, Henrik Ortsäter, Pierre Scotney, Daniel Nyqvist, Erik Samén, Li Lu, Sharon Stone-Elander, Joseph Proietto, Sofianos Andrikopoulos, Åke Sjöholm, Andrew Nash and Ulf Eriksson ()
Additional contact information
Carolina E. Hagberg: Tissue Biology Group, Karolinska Institutet, SE-171 77 Stockholm, Sweden
Annika Mehlem: Tissue Biology Group, Karolinska Institutet, SE-171 77 Stockholm, Sweden
Annelie Falkevall: Tissue Biology Group, Karolinska Institutet, SE-171 77 Stockholm, Sweden
Lars Muhl: Tissue Biology Group, Karolinska Institutet, SE-171 77 Stockholm, Sweden
Barbara C. Fam: University of Melbourne
Henrik Ortsäter: Diabetes Research Unit, Södersjukhuset, Karolinska Institutet
Pierre Scotney: CSL Limited
Daniel Nyqvist: Tissue Biology Group, Karolinska Institutet, SE-171 77 Stockholm, Sweden
Erik Samén: Karolinska University Hospital
Li Lu: Karolinska University Hospital
Sharon Stone-Elander: Karolinska University Hospital
Joseph Proietto: University of Melbourne
Sofianos Andrikopoulos: University of Melbourne
Åke Sjöholm: Diabetes Research Unit, Södersjukhuset, Karolinska Institutet
Andrew Nash: CSL Limited
Ulf Eriksson: Tissue Biology Group, Karolinska Institutet, SE-171 77 Stockholm, Sweden

Nature, 2012, vol. 490, issue 7420, 426-430

Abstract: Inhibition of VEGF-B signalling is shown to limit ectopic fatty-acid accumulation, restore peripheral insulin sensitivity and muscle glucose uptake, and preserve pancreatic islet functionality.

Date: 2012
References: Add references at CitEc
Citations:

Downloads: (external link)
https://www.nature.com/articles/nature11464 Abstract (text/html)
Access to the full text of the articles in this series is restricted.

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:nat:nature:v:490:y:2012:i:7420:d:10.1038_nature11464

Ordering information: This journal article can be ordered from
https://www.nature.com/

DOI: 10.1038/nature11464

Access Statistics for this article

Nature is currently edited by Magdalena Skipper

More articles in Nature from Nature
Bibliographic data for series maintained by Sonal Shukla () and Springer Nature Abstracting and Indexing ().