Bacterial virulence proteins as tools to rewire kinase pathways in yeast and immune cells

Ping Wei, Wilson W. Wong, Jason S. Park, Ethan E. Corcoran, Sergio G. Peisajovich, James J. Onuffer, Arthur Weiss and Wendell A. Lim ()
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Ping Wei: University of California San Francisco
Wilson W. Wong: University of California San Francisco
Jason S. Park: University of California San Francisco
Ethan E. Corcoran: Howard Hughes Medical Institute, University of California San Francisco
Sergio G. Peisajovich: University of California San Francisco
James J. Onuffer: University of California San Francisco
Arthur Weiss: Howard Hughes Medical Institute, University of California San Francisco
Wendell A. Lim: University of California San Francisco

Nature, 2012, vol. 488, issue 7411, 384-388

Abstract: Virulence factors from two bacteria are used to reprogram intracellular signalling in yeast and immune T cells, illustrating how pathogens can provide a toolkit to engineer cells for biotechnological or therapeutic applications.

Date: 2012
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DOI: 10.1038/nature11259

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