Kill the messenger where it lives

Peter K. Todd () and Henry L. Paulson ()
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Peter K. Todd: University of Michigan, Ann Arbor, Michigan 48109, USA.
Henry L. Paulson: University of Michigan, Ann Arbor, Michigan 48109, USA.

Nature, 2012, vol. 488, issue 7409, 36-37

Abstract: A mutant repeating DNA sequence produces a toxic RNA molecule that causes the neuromuscular disorder myotonic dystrophy type 1. An ‘antisense’ therapy that targets this RNA in cell nuclei shows promise in mice. See Letter p.111

Date: 2012
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DOI: 10.1038/488036a

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