HVEM signalling at mucosal barriers provides host defence against pathogenic bacteria

Jr-Wen Shui, Alexandre Larange, Gisen Kim, Jose Luis Vela, Sonja Zahner, Hilde Cheroutre and Mitchell Kronenberg ()
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Jr-Wen Shui: La Jolla Institute for Allergy and Immunology, 9420 Athena Circle, La Jolla, California 92037, USA
Alexandre Larange: La Jolla Institute for Allergy and Immunology, 9420 Athena Circle, La Jolla, California 92037, USA
Gisen Kim: La Jolla Institute for Allergy and Immunology, 9420 Athena Circle, La Jolla, California 92037, USA
Jose Luis Vela: La Jolla Institute for Allergy and Immunology, 9420 Athena Circle, La Jolla, California 92037, USA
Sonja Zahner: La Jolla Institute for Allergy and Immunology, 9420 Athena Circle, La Jolla, California 92037, USA
Hilde Cheroutre: La Jolla Institute for Allergy and Immunology, 9420 Athena Circle, La Jolla, California 92037, USA
Mitchell Kronenberg: La Jolla Institute for Allergy and Immunology, 9420 Athena Circle, La Jolla, California 92037, USA

Nature, 2012, vol. 488, issue 7410, 222-225

Abstract: The TNF receptor HVEM is shown to control the innate immune response to pathogenic bacteria by regulating mucosal epithelial cells in the intestine and lung.

Date: 2012
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DOI: 10.1038/nature11242

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