A basal ganglia circuit for evaluating action outcomes

Marcus Stephenson-Jones (), Kai Yu, Sandra Ahrens, Jason M. Tucciarone, Aile N. van Huijstee, Luis A. Mejia, Mario A. Penzo, Lung-Hao Tai, Linda Wilbrecht and Bo Li ()
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Marcus Stephenson-Jones: Cold Spring Harbor Laboratory, Cold Spring Harbor
Kai Yu: Cold Spring Harbor Laboratory, Cold Spring Harbor
Sandra Ahrens: Cold Spring Harbor Laboratory, Cold Spring Harbor
Jason M. Tucciarone: Cold Spring Harbor Laboratory, Cold Spring Harbor
Aile N. van Huijstee: Cold Spring Harbor Laboratory, Cold Spring Harbor
Luis A. Mejia: Cold Spring Harbor Laboratory, Cold Spring Harbor
Mario A. Penzo: Cold Spring Harbor Laboratory, Cold Spring Harbor
Lung-Hao Tai: University of California Berkeley, Berkeley
Linda Wilbrecht: University of California Berkeley, Berkeley
Bo Li: Cold Spring Harbor Laboratory, Cold Spring Harbor

Nature, 2016, vol. 539, issue 7628, 289-293

Abstract: In mice, glutamatergic globus pallidus neurons projecting to the lateral habenula (GPh neurons) bi-directionally encode positive and negative prediction error signals that are critical for outcome evaluation and are driven by a subset of basal ganglia circuits.

Date: 2016
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DOI: 10.1038/nature19845

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