Mechanism of super-assembly of respiratory complexes III and IV

Sara Cogliati, Enrique Calvo, Marta Loureiro, Adela M. Guaras, Rocio Nieto-Arellano, Carolina Garcia-Poyatos, Iakes Ezkurdia, Nadia Mercader, Jesús Vázquez () and José Antonio Enriquez ()
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Sara Cogliati: Centro Nacional de Investigaciones Cardiovasculares Carlos III
Enrique Calvo: Centro Nacional de Investigaciones Cardiovasculares Carlos III
Marta Loureiro: Centro Nacional de Investigaciones Cardiovasculares Carlos III
Adela M. Guaras: Centro Nacional de Investigaciones Cardiovasculares Carlos III
Rocio Nieto-Arellano: Centro Nacional de Investigaciones Cardiovasculares Carlos III
Carolina Garcia-Poyatos: Centro Nacional de Investigaciones Cardiovasculares Carlos III
Iakes Ezkurdia: Centro Nacional de Investigaciones Cardiovasculares Carlos III
Nadia Mercader: Centro Nacional de Investigaciones Cardiovasculares Carlos III
Jesús Vázquez: Centro Nacional de Investigaciones Cardiovasculares Carlos III
José Antonio Enriquez: Centro Nacional de Investigaciones Cardiovasculares Carlos III

Nature, 2016, vol. 539, issue 7630, 579-582

Abstract: SCAF1 is always required for the interaction between the respiratory chain complexes III and IV, and in animals carrying only the short isoform of SCAF1, the respirasome is absent in most tissues, with the exception of heart and skeletal muscle, where COX7A2 is present instead of SCAF1.

Date: 2016
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DOI: 10.1038/nature20157

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