Evolution of Hoxa11 regulation in vertebrates is linked to the pentadactyl state

Yacine Kherdjemil, Robert L. Lalonde, Rushikesh Sheth, Annie Dumouchel, Gemma de Martino, Kyriel M. Pineault, Deneen M. Wellik, H. Scott Stadler, Marie-Andrée Akimenko and Marie Kmita ()
Additional contact information
Yacine Kherdjemil: Genetics and Development Research Unit, Institut de Recherches Cliniques de Montréal
Robert L. Lalonde: University of Ottawa
Rushikesh Sheth: Genetics and Development Research Unit, Institut de Recherches Cliniques de Montréal
Annie Dumouchel: Genetics and Development Research Unit, Institut de Recherches Cliniques de Montréal
Gemma de Martino: Genetics and Development Research Unit, Institut de Recherches Cliniques de Montréal
Kyriel M. Pineault: University of Michigan
Deneen M. Wellik: University of Michigan
H. Scott Stadler: Shriners Hospital for Children
Marie-Andrée Akimenko: University of Ottawa
Marie Kmita: Genetics and Development Research Unit, Institut de Recherches Cliniques de Montréal

Nature, 2016, vol. 539, issue 7627, 89-92

Abstract: The mutually exclusive expression of the Hoxa11 and Hoxa13 genes is required for pentadactyl (five-digit) limbs and is proposed to have contributed to the transition from several digits polydactyl (several-digit) limbs in the earliest tetrapods.

Date: 2016
References: Add references at CitEc
Citations: View citations in EconPapers (2)

Downloads: (external link)
https://www.nature.com/articles/nature19813 Abstract (text/html)
Access to the full text of the articles in this series is restricted.

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:nat:nature:v:539:y:2016:i:7627:d:10.1038_nature19813

Ordering information: This journal article can be ordered from
https://www.nature.com/

DOI: 10.1038/nature19813

Access Statistics for this article

Nature is currently edited by Magdalena Skipper

More articles in Nature from Nature
Bibliographic data for series maintained by Sonal Shukla () and Springer Nature Abstracting and Indexing ().