Retraction Note: Systemic signals regulate ageing and rejuvenation of blood stem cell niches

Shane R. Mayack, Jennifer L. Shadrach, Francis S. Kim and Amy J. Wagers

Nature, 2010, vol. 467, issue 7317, 872-872

Abstract: Three of the authors (J.L.S., F.S.K. and A.J.W.) wish to retract this Article after a re-examination of the publication raised serious concerns with some of the reported data. These concerns have undermined the authors’ confidence in the support for the scientific conclusions reported, specifically the role of osteopontin-positive niche cells in the rejuvenation of haematopoietic stem cells in aged mice.

Date: 2010
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DOI: 10.1038/nature09474

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