Longer-lived proteins

Jeffrey A. Hubbell
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Jeffrey A. Hubbell: Jeffrey A. Hubbell is at the Institute of Bioengineering and the Institute of Chemical Sciences and Engineering, Ecole Polytechnique Fédérale de Lausanne (EPFL), CH-1015 Lausanne, Switzerland. jeffrey.hubbell@epfl.ch

Nature, 2010, vol. 467, issue 7319, 1051-1052

Abstract: Short residence times in the bloodstream reduce the effectiveness of protein drugs. Application of an approach that combines protein and polymer engineering prolongs circulation time and increases drug uptake by tumours.

Date: 2010
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DOI: 10.1038/4671051a

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