Newly made mitochondrial DNA drives inflammation

Michael P. Murphy ()

Nature, 2018, vol. 560, issue 7717, 176-177

Abstract: Activation of the inflammasome protein complex in immune cells is a key step that triggers an innate immune response. It emerges that the synthesis and oxidation of mitochondrial DNA drives this activation step.

Keywords: Cell biology; Immunology (search for similar items in EconPapers)
Date: 2018
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DOI: 10.1038/d41586-018-05764-z

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