Two-layer design protects genes from mutations in their enhancers

Ran Elkon () and Reuven Agami ()

Nature, 2022, vol. 609, issue 7927, 477-478

Abstract: Gene expression is regulated by clusters of regulatory DNA sequences called enhancers. Basic design principles that protect enhancer networks against the harmful effects of genetic mutations have now been elucidated.

Keywords: Epigenetics; Genetics (search for similar items in EconPapers)
Date: 2022
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DOI: 10.1038/d41586-022-02341-3

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