Structural keys unlock RAS–MAPK cellular signalling pathway

Hugo Lavoie () and Marc Therrien ()

Nature, 2022, vol. 609, issue 7926, 248-249

Abstract: Activation of the RAF protein is key to the RAS–MAPK signalling pathway, and involves the SMP protein complex. Structures for SMP shed light on the process, and suggest fresh targets for anticancer drug discovery.

Keywords: Structural biology; Molecular biology (search for similar items in EconPapers)
Date: 2022
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DOI: 10.1038/d41586-022-02189-7

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