Eggs made from male mouse stem cells using error-prone culture

Jonathan Bayerl and Diana J. Laird ()

Nature, 2023, vol. 615, issue 7954, 805-807

Abstract: A screen of mouse stem cells that exploits their propensity to gain or lose chromosomes in cell culture has been used to convert male XY to female XX cells. Subsequent differentiation generates functional eggs and live offspring.

Keywords: Developmental biology; Stem cells; Biological techniques (search for similar items in EconPapers)
Date: 2023
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DOI: 10.1038/d41586-023-00755-1

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