Dynamics of ribosome scanning and recycling revealed by translation complex profiling

Stuart K. Archer, Nikolay E. Shirokikh, Traude H. Beilharz and Thomas Preiss ()
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Stuart K. Archer: EMBL–Australia Collaborating Group, The John Curtin School of Medical Research, The Australian National University
Nikolay E. Shirokikh: EMBL–Australia Collaborating Group, The John Curtin School of Medical Research, The Australian National University
Traude H. Beilharz: Development and Stem Cells Program, Monash University
Thomas Preiss: EMBL–Australia Collaborating Group, The John Curtin School of Medical Research, The Australian National University

Nature, 2016, vol. 535, issue 7613, 570-574

Abstract: A translation complex sequencing approach has been developed enabling intermediates of all mRNA-associated processes of translation to be isolated and localized across the transcriptome; the results support longstanding models of initiation and termination and offer new mechanistic insights.

Date: 2016
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DOI: 10.1038/nature18647

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