Identification of proliferative and mature β-cells in the islets of Langerhans

Erik Bader, Adriana Migliorini, Moritz Gegg, Noah Moruzzi, Jantje Gerdes, Sara S. Roscioni, Mostafa Bakhti, Elisabeth Brandl, Martin Irmler, Johannes Beckers, Michaela Aichler, Annette Feuchtinger, Christin Leitzinger, Hans Zischka, Rui Wang-Sattler, Martin Jastroch, Matthias Tschöp, Fausto Machicao, Harald Staiger, Hans-Ulrich Häring, Helena Chmelova, Julie A. Chouinard, Nikolay Oskolkov, Olle Korsgren, Stephan Speier and Heiko Lickert ()
Additional contact information
Erik Bader: Institute of Diabetes and Regeneration Research, Helmholtz Zentrum München
Adriana Migliorini: Institute of Diabetes and Regeneration Research, Helmholtz Zentrum München
Moritz Gegg: Institute of Diabetes and Regeneration Research, Helmholtz Zentrum München
Noah Moruzzi: Institute of Diabetes and Regeneration Research, Helmholtz Zentrum München
Jantje Gerdes: Institute of Diabetes and Regeneration Research, Helmholtz Zentrum München
Sara S. Roscioni: Institute of Diabetes and Regeneration Research, Helmholtz Zentrum München
Mostafa Bakhti: Institute of Diabetes and Regeneration Research, Helmholtz Zentrum München
Elisabeth Brandl: Institute of Diabetes and Regeneration Research, Helmholtz Zentrum München
Martin Irmler: German Center for Diabetes Research (DZD)
Johannes Beckers: German Center for Diabetes Research (DZD)
Michaela Aichler: Research Unit Analytical Pathology, Helmholtz Zentrum München
Annette Feuchtinger: Research Unit Analytical Pathology, Helmholtz Zentrum München
Christin Leitzinger: Institute of Molecular Toxicology and Pharmacology, Helmholtz Zentrum München
Hans Zischka: Institute of Molecular Toxicology and Pharmacology, Helmholtz Zentrum München
Rui Wang-Sattler: Institute of Epidemiology II, Helmholtz Zentrum München
Martin Jastroch: German Center for Diabetes Research (DZD)
Matthias Tschöp: German Center for Diabetes Research (DZD)
Fausto Machicao: German Center for Diabetes Research (DZD)
Harald Staiger: German Center for Diabetes Research (DZD)
Hans-Ulrich Häring: German Center for Diabetes Research (DZD)
Helena Chmelova: German Center for Diabetes Research (DZD)
Julie A. Chouinard: German Center for Diabetes Research (DZD)
Nikolay Oskolkov: Diabetes and Endocrinology, Lund University Diabetes Centre
Olle Korsgren: Genetics and Pathology, Uppsala University
Stephan Speier: German Center for Diabetes Research (DZD)
Heiko Lickert: Institute of Diabetes and Regeneration Research, Helmholtz Zentrum München

Nature, 2016, vol. 535, issue 7612, 430-434

Abstract: Mature pancreatic β-cells can be distinguished from proliferating ones by expression of the Fltp reporter gene, which is triggered by Wnt signalling and β-cell polarization and islet compaction.

Date: 2016
References: Add references at CitEc
Citations:

Downloads: (external link)
https://www.nature.com/articles/nature18624 Abstract (text/html)
Access to the full text of the articles in this series is restricted.

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:nat:nature:v:535:y:2016:i:7612:d:10.1038_nature18624

Ordering information: This journal article can be ordered from
https://www.nature.com/

DOI: 10.1038/nature18624

Access Statistics for this article

Nature is currently edited by Magdalena Skipper

More articles in Nature from Nature
Bibliographic data for series maintained by Sonal Shukla () and Springer Nature Abstracting and Indexing ().