Glial-cell-derived neuroregulators control type 3 innate lymphoid cells and gut defence

Sales Ibiza, Bethania García-Cassani, Hélder Ribeiro, Tânia Carvalho, Luís Almeida, Rute Marques, Ana M. Misic, Casey Bartow-McKenney, Denise M. Larson, William J. Pavan, Gérard Eberl, Elizabeth A. Grice and Henrique Veiga-Fernandes ()
Additional contact information
Sales Ibiza: Instituto de Medicina Molecular, Faculdade de Medicina de Lisboa, Av. Prof. Egas Moniz, Edifício Egas Moniz
Bethania García-Cassani: Instituto de Medicina Molecular, Faculdade de Medicina de Lisboa, Av. Prof. Egas Moniz, Edifício Egas Moniz
Hélder Ribeiro: Instituto de Medicina Molecular, Faculdade de Medicina de Lisboa, Av. Prof. Egas Moniz, Edifício Egas Moniz
Tânia Carvalho: Instituto de Medicina Molecular, Faculdade de Medicina de Lisboa, Av. Prof. Egas Moniz, Edifício Egas Moniz
Luís Almeida: Instituto de Medicina Molecular, Faculdade de Medicina de Lisboa, Av. Prof. Egas Moniz, Edifício Egas Moniz
Rute Marques: Microenvironment and Immunity Unit, Institut Pasteur
Ana M. Misic: Perelman School of Medicine, University of Pennsylvania, 421 Curie Blvd
Casey Bartow-McKenney: Perelman School of Medicine, University of Pennsylvania, 421 Curie Blvd
Denise M. Larson: Genetic Disease Research Branch, National Human Genome Research Institute, National Institutes of Health
William J. Pavan: Genetic Disease Research Branch, National Human Genome Research Institute, National Institutes of Health
Gérard Eberl: Microenvironment and Immunity Unit, Institut Pasteur
Elizabeth A. Grice: Perelman School of Medicine, University of Pennsylvania, 421 Curie Blvd
Henrique Veiga-Fernandes: Instituto de Medicina Molecular, Faculdade de Medicina de Lisboa, Av. Prof. Egas Moniz, Edifício Egas Moniz

Nature, 2016, vol. 535, issue 7612, 440-443

Abstract: Neurotrophic factors produced by enteric glia in response to microbiota and alarmin cues regulate IL-22 production by group 3 innate lymphoid cells in the gut; disruption of this pathway leads to impaired clearance of Citrobacter rodentium and defects in epithelial integrity in a model of intestinal inflammation.

Date: 2016
References: Add references at CitEc
Citations: View citations in EconPapers (2)

Downloads: (external link)
https://www.nature.com/articles/nature18644 Abstract (text/html)
Access to the full text of the articles in this series is restricted.

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:nat:nature:v:535:y:2016:i:7612:d:10.1038_nature18644

Ordering information: This journal article can be ordered from
https://www.nature.com/

DOI: 10.1038/nature18644

Access Statistics for this article

Nature is currently edited by Magdalena Skipper

More articles in Nature from Nature
Bibliographic data for series maintained by Sonal Shukla () and Springer Nature Abstracting and Indexing ().