Mitochondrial DNA in evolution and disease

Douglas C. Wallace ()
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Douglas C. Wallace: Douglas C. Wallace is in the Center for Mitochondrial and Epigenomic Medicine, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA, University of Pennsylvania.

Nature, 2016, vol. 535, issue 7613, 498-500

Abstract: Cellular organelles called mitochondria contain their own DNA. The discovery that variation in mitochondrial DNA alters physiology and lifespan in mice has implications for evolutionary biology and the origins of disease. See Letter p.561

Date: 2016
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DOI: 10.1038/nature18902

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