A new heart for a new head in vertebrate cardiopharyngeal evolution

Rui Diogo (), Robert G. Kelly (), Lionel Christiaen (), Michael Levine, Janine M. Ziermann, Julia L. Molnar, Drew M. Noden and Eldad Tzahor ()
Additional contact information
Rui Diogo: Howard University College of Medicine
Robert G. Kelly: Aix Marseille Université, Centre National de la Recherche Scientifique, Institut de Biologie du Développement de Marseille UMR 7288
Lionel Christiaen: Center for Developmental Genetics, New York University
Michael Levine: University of California at Berkeley, California 94720, USA.
Janine M. Ziermann: Howard University College of Medicine
Julia L. Molnar: Howard University College of Medicine
Drew M. Noden: College of Veterinary Medicine, Cornell University
Eldad Tzahor: Weizmann Institute of Science

Nature, 2015, vol. 520, issue 7548, 466-473

Abstract: Abstract It has been more than 30 years since the publication of the new head hypothesis, which proposed that the vertebrate head is an evolutionary novelty resulting from the emergence of neural crest and cranial placodes. Neural crest generates the skull and associated connective tissues, whereas placodes produce sensory organs. However, neither crest nor placodes produce head muscles, which are a crucial component of the complex vertebrate head. We discuss emerging evidence for a surprising link between the evolution of head muscles and chambered hearts — both systems arise from a common pool of mesoderm progenitor cells within the cardiopharyngeal field of vertebrate embryos. We consider the origin of this field in non-vertebrate chordates and its evolution in vertebrates.

Date: 2015
References: Add references at CitEc
Citations: View citations in EconPapers (6)

Downloads: (external link)
https://www.nature.com/articles/nature14435 Abstract (text/html)
Access to the full text of the articles in this series is restricted.

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:nat:nature:v:520:y:2015:i:7548:d:10.1038_nature14435

Ordering information: This journal article can be ordered from
https://www.nature.com/

DOI: 10.1038/nature14435

Access Statistics for this article

Nature is currently edited by Magdalena Skipper

More articles in Nature from Nature
Bibliographic data for series maintained by Sonal Shukla () and Springer Nature Abstracting and Indexing ().