ATG14 promotes membrane tethering and fusion of autophagosomes to endolysosomes

Jiajie Diao, Rong Liu, Yueguang Rong, Minglei Zhao, Jing Zhang, Ying Lai, Qiangjun Zhou, Livia M. Wilz, Jianxu Li, Sandro Vivona, Richard A. Pfuetzner, Axel T. Brunger and Qing Zhong ()
Additional contact information
Jiajie Diao: Stanford University
Rong Liu: Center for Autophagy Research, University of Texas Southwestern Medical Center
Yueguang Rong: Center for Autophagy Research, University of Texas Southwestern Medical Center
Minglei Zhao: Stanford University
Jing Zhang: Center for Autophagy Research, University of Texas Southwestern Medical Center
Ying Lai: Stanford University
Qiangjun Zhou: Stanford University
Livia M. Wilz: Biophysics and Structural Biology, University of California at Berkeley
Jianxu Li: Biophysics and Structural Biology, University of California at Berkeley
Sandro Vivona: Stanford University
Richard A. Pfuetzner: Stanford University
Axel T. Brunger: Stanford University
Qing Zhong: Center for Autophagy Research, University of Texas Southwestern Medical Center

Nature, 2015, vol. 520, issue 7548, 563-566

Abstract: The essential autophagy mediator ATG14 promotes vesicle fusion by forming homo-oligomers, which bind to a component of the SNARE membrane fusion complex and stabilize this complex on autophagosomes.

Date: 2015
References: Add references at CitEc
Citations: View citations in EconPapers (6)

Downloads: (external link)
https://www.nature.com/articles/nature14147 Abstract (text/html)
Access to the full text of the articles in this series is restricted.

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:nat:nature:v:520:y:2015:i:7548:d:10.1038_nature14147

Ordering information: This journal article can be ordered from
https://www.nature.com/

DOI: 10.1038/nature14147

Access Statistics for this article

Nature is currently edited by Magdalena Skipper

More articles in Nature from Nature
Bibliographic data for series maintained by Sonal Shukla () and Springer Nature Abstracting and Indexing ().