Intrinsic light response of retinal horizontal cells of teleosts

Ning Cheng (), Takashi Tsunenari and King-Wai Yau ()
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Ning Cheng: Solomon H. Snyder Department of Neuroscience,
Takashi Tsunenari: Solomon H. Snyder Department of Neuroscience,
King-Wai Yau: Solomon H. Snyder Department of Neuroscience,

Nature, 2009, vol. 460, issue 7257, 899-903

Abstract: Photosensitive horizontal cells in fish retina It has recently become apparent that the familiar rods and cones are not the only photoreceptors in mammals — a third class known as intrinsically photosensitive retinal ganglion cells (ipRGCs) are now known to relay light information that synchronizes circadian rhythms and triggers the papillary light reflex. Here, Cheng et al. show that a subset of retinal horizontal cells in teleost fish is also photosensitive. Like mammalian ipRGCs, the photopigment that confers photosensitivity in this subset of vertebrate horizontal cells appears to be melanopsin.

Date: 2009
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DOI: 10.1038/nature08175

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