The promises and perils of p53

Valery Krizhanovsky and Scott W. Lowe
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Valery Krizhanovsky: Valery Krizhanovsky and Scott W. Lowe are in the Cold Spring Harbor Laboratory and Howard Hughes Medical Institute, Cold Spring Harbor, New York 11724, USA.
Scott W. Lowe: Valery Krizhanovsky and Scott W. Lowe are in the Cold Spring Harbor Laboratory and Howard Hughes Medical Institute, Cold Spring Harbor, New York 11724, USA.

Nature, 2009, vol. 460, issue 7259, 1085-1086

Abstract: Five studies show that disabling p53, an essential tumour-suppressor protein, improves the efficiency of stem-cell production. Are these results a 'heads up' that cancer cells and stem cells are disturbingly similar?

Date: 2009
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DOI: 10.1038/4601085a

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