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E. Richard Moxon and David S. Thaler
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E. Richard Moxon: John Radcliffe Hospital
David S. Thaler: Sackler Laboratory of Molecular Genetics and Informatics, The Rockefeller University

Nature, 1997, vol. 387, issue 6634, 659-662

Abstract: By knowing the mechanisms through which genetic variants are generated, we should gain a better understanding of evolution. Two new papers — one theoretical and one experimental — show that mutator alleles (which can lead to a huge increase in mutation rate) can speed up the rate at which bacteria adapt to a changing environment, even if these alleles remain at a low frequency.

Date: 1997
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DOI: 10.1038/42607

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