Double identity for proteins of the Bcl-2 family

John C. Reed
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John C. Reed: Burnham Institute, Program on Apoptosis and Cell Death Research

Nature, 1997, vol. 387, issue 6635, 773-776

Abstract: Abstract Bcl-2 is an oncogenic protein that acts by inhibiting programmed cell death. The mechanisms used by this and related anti-apoptotic proteins to protect cells from cytotoxic stimuli are now emerging, with the discovery that Bcl-2 can function both as an ion channel and as an adaptor or docking protein.

Date: 1997
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DOI: 10.1038/42867

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