The awakening of α-synuclein

Michel Goedert
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Michel Goedert: Medical Research Council Laboratory of Molecular Biology

Nature, 1997, vol. 388, issue 6639, 232-233

Abstract: Parkinson's disease occurs in a rare familial (inherited) form. At long last researchers have identified a gene which, when mutated, is at least in part responsible for the condition — the mutation changes the amino acid alanine to threonine at a particular position in a protein called a-synuclein. It remains to be seen whether this finding will tell us more about the much more common sporadic form of the disease.

Date: 1997
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DOI: 10.1038/40767

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