Metallothionein in snail Cd and Cu metabolism

Reinhard Dallinger, Burkhard Berger, Peter Hunziger and Jeremias H. R. Kgi
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Reinhard Dallinger: Institut für Zoologie und Limnologie, Universität Innsbruck
Burkhard Berger: Institut für Zoologie und Limnologie, Universität Innsbruck
Peter Hunziger: Biochemisches Institut der Universität Zürich
Jeremias H. R. Kgi: Biochemisches Institut der Universität Zürich

Nature, 1997, vol. 388, issue 6639, 237-238

Abstract: Abstract Terrestrial snails tolerate elevated concentrations of cadmium and copper, accumulating both metals in their soft tissues1. The snails are able to inactivate the toxic cadmium while meeting their metabolic requirement for copper. Here we report evidence for the metabolic discrimination between the two metals based on the existence of distinct metallothionein isoforms, one dedicated to cadmium detoxification and another to copper regulation.

Date: 1997
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DOI: 10.1038/40785

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