A personal thermostat

David Jones

Nature, 1997, vol. 388, issue 6640, 333-333

Abstract: The body's central-heating system is flawed, in that in chilly climates people need to wear clothes or use fires for extra warmth. A plan to improve on the system involves identifying a glucose-oxidizing enzyme which works well in the cold but becomes reversibly denatured at 37 °C — human body temperature. When immobilized on microspheres and injected into the blood, the enzyme will become activated on reaching the cold outer extremities of the body. There it will burn glucose, warming the skin and acting as a perfect distributed body thermostat.

Date: 1997
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DOI: 10.1038/40992

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