Long-distance long-term depression

Roger A. Nicoll and Robert C. Malenka
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Roger A. Nicoll: University of California
Robert C. Malenka: University of California

Nature, 1997, vol. 388, issue 6641, 427-428

Abstract: Long-lasting changes in the strength of synapses in the brain underlie many forms of learning and memory. Depending on the pattern of activation, synapses can show either long-term potentiation (LTP) or long-term depression (LTD). A provocative study now shows that a form of LTD may spread over considerable distances, and that this spread may even involve signals that travel backwards.

Date: 1997
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DOI: 10.1038/41222

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