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Stochastic resonance at the single-cell level

Sergey M. Bezrukov () and Igor Vodyanoy
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Sergey M. Bezrukov: National Institutes of Health
Igor Vodyanoy: National Institutes of Health

Nature, 1997, vol. 388, issue 6643, 633-633

Abstract: Abstract Bezrukov and Vodyanoy reply — The possibility that the mechanism of stochastic resonance might account for the sensitivity of organisms to industrial low-frequency magnetic and/or electric fields has inspired much discussion1,2,10. In a recent Letter6 we formulated a physical model of stochastic resonance that permits quantitative analysis of the phenomenon in a variety of systems. Astumian and co-workers apply our results to the intriguing but difficult question of the role of stochastic resonance in signal detection at the level of a single cell. For a ‘typical cell’ of 100 μm radius, they come to a conclusion that stochastic resonance increases cell sensitivity to small signals,but that this increase is not significant enough to account for the effects reported by others2. Although we agree with their treatment of our theory, we show that for smaller cells stochastic resonance can improve signal detection considerably.

Date: 1997
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DOI: 10.1038/41688

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