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Histone acetylation in chromatin structure and transcription

Michael Grunstein
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Michael Grunstein: UCLA School of Medicine and the Molecular Biology Institute, University of California

Nature, 1997, vol. 389, issue 6649, 349-352

Abstract: Abstract The amino termini of histones extend from the nucleosomal core and are modified by acetyltransferases and deacetylases during the cell cycle. These acetylation patterns may direct histone assembly and help regulate the unfolding and activity of genes.

Date: 1997
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DOI: 10.1038/38664

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