Feedback from inhibitory SMADs

Malcolm Whitman ()
Additional contact information
Malcolm Whitman: Harvard Medical School

Nature, 1997, vol. 389, issue 6651, 549-551

Abstract: Many biological processes involve signalling through the transforming growth factor-b (TGF-β) superfamily of proteins. In some pathways, TGF-b signals are mediated through the SMAD family of signal transducers. Smads 1, 2, 3 and 5 are activated when members of the TGF-b family bind their receptors, leading to association with Smad4 and a transcriptional response. Three groups now independently show that two new SMADs (Smads 6 and 7) and a Drosophila homologue inhibit this signalling process.

Date: 1997
References: Add references at CitEc
Citations:

Downloads: (external link)
https://www.nature.com/articles/39202 Abstract (text/html)
Access to the full text of the articles in this series is restricted.

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:nat:nature:v:389:y:1997:i:6651:d:10.1038_39202

Ordering information: This journal article can be ordered from
https://www.nature.com/

DOI: 10.1038/39202

Access Statistics for this article

Nature is currently edited by Magdalena Skipper

More articles in Nature from Nature
Bibliographic data for series maintained by Sonal Shukla () and Springer Nature Abstracting and Indexing ().