The ins and outs of amyloid-β

Konrad Beyreuther () and Colin L. Masters
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Konrad Beyreuther: the ZMBH, University of Heidelberg
Colin L. Masters: the University of Melbourne

Nature, 1997, vol. 389, issue 6652, 677-678

Abstract: The extracellular plaques of amyloid-b (Ab) peptide that form in the brains of pateints with Alzheimer's disease are thought to be involved in neurodegeneration but, until now, nobody was sure how Ab interfered with neuronal function. The finding that Ab interacts with the newly discovered endoplasmic-reticulum-associated binding protein (ERAB) in neurons may help to solve this puzzle.

Date: 1997
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DOI: 10.1038/39479

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