Myosin trapped but not tamed

Clive R. Bagshaw ()
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Clive R. Bagshaw: University of Leicester

Nature, 1997, vol. 390, issue 6658, 345-346

Abstract: Muscles contain interdigitating filaments of actin and myosin, which are connected by cross-bridges (myosin heads) driven by ATP hydrolysis. What goes on in molecular terms during muscle contraction remains a matter of debate, however, and was the topic of a European meeting in September. Discussion centred on crystal structures of the cross-bridge and actin at atomic resolution, and the development of assays to follow events at the single-molecule level. Fresh ways of looking at muscle disease also came in for consideration.

Date: 1997
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DOI: 10.1038/37002

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