Teaming up to restrain cancer
Moshe Oren ()
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Moshe Oren: The Weizmann Institute of Science
Nature, 1998, vol. 391, issue 6664, 233-234
Abstract:
Tumour-suppressor genes such asp53 serve as potent buffers against uncontrolled cell multiplication and cancer. But it now seems that they do not work alone. Another tumour-suppressor protein, p33ING1, has been found to form a direct complex with p53. And it seems that each of the proteins requires the other to exert its inhibitory effects.
Date: 1998
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DOI: 10.1038/34551
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