A new classification for HIV-1

E. A. Berger, R. W. Doms, E.-M. Fenyö, B. T. M. Korber, D. R. Littman, J. P. Moore, Q. J. Sattentau, H. Schuitemaker, J. Sodroski and R. A. Weiss
Additional contact information
E. A. Berger: Laboratory of Viral Diseases, NIAID, National Institutes of Health
R. W. Doms: University of Pennsylvania
E.-M. Fenyö: EC Concerted Action on HIV Variation, Microbiology and Tumorbiology Center, Karolinska Institute
B. T. M. Korber: Theoretical Biology and Biophysics, Los Alamos National Laboratory
D. R. Littman: Howard Hughes Medical Institute, New York University Medical Center
J. P. Moore: The Aaron Diamond AIDS Research Center, The Rockefeller University
Q. J. Sattentau: Centre dImmunologie de Marseille-Luminy
H. Schuitemaker: Central Laboratory of the Netherlands Red Cross Blood Transfusion Service and Laboratory for Experimental and Clinical Immunology, University of Amsterdam
J. Sodroski: Dana-Farber Cancer Institute
R. A. Weiss: Chester Beatty Laboratories, The Institute of Cancer Research

Nature, 1998, vol. 391, issue 6664, 240-240

Abstract: Abstract The phenotype of HIV-1 isolates is defined by the cells in which they replicate in vitro, but these phenotypes can change in vivo with profound implications for viral transmission, pathogenesis and disease progression. Here we propose a new classification system based on co-receptor use, providing a more accurate description of viral phenotype than the present imprecise and often misleading classification schemes.

Date: 1998
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DOI: 10.1038/34571

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