CCR5 is characteristic of Th1 lymphocytes

Pius Loetscher (), Mariagrazia Uguccioni, Lorenza Bordoli, Marco Baggiolini, Bernhard Moser, Carlo Chizzolini and Jean-Michel Dayer
Additional contact information
Pius Loetscher: University Hospital
Mariagrazia Uguccioni: Theodor-Kocher Institute, University of Bern
Lorenza Bordoli: Theodor-Kocher Institute, University of Bern
Marco Baggiolini: Theodor-Kocher Institute, University of Bern
Bernhard Moser: Theodor-Kocher Institute, University of Bern
Carlo Chizzolini: University Hospital
Jean-Michel Dayer: University Hospital

Nature, 1998, vol. 391, issue 6665, 344-345

Abstract: Abstract CD4+ lymphocytes can be assigned to two subsets1. Th1 lymphocytes secrete interferon gamma (IFNγ) and lymphotoxin, promoting cell-mediated immunity to intracellular pathogens; and Th2 lymphocytes secrete interleukins 4 and 5 (IL-4 and IL-5), which function in allergy and humoral immunity to parasites. Th2 lymphocytes preferentially express the chemokine receptor CCR3 (23). We have studied the occurrence of two additional chemokine receptors, CCR5 and CXCR3, in human, antigen-specific CD4+ Th1 and Th2 cell clones4.

Date: 1998
References: Add references at CitEc
Citations:

Downloads: (external link)
https://www.nature.com/articles/34814 Abstract (text/html)
Access to the full text of the articles in this series is restricted.

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:nat:nature:v:391:y:1998:i:6665:d:10.1038_34814

Ordering information: This journal article can be ordered from
https://www.nature.com/

DOI: 10.1038/34814

Access Statistics for this article

Nature is currently edited by Magdalena Skipper

More articles in Nature from Nature
Bibliographic data for series maintained by Sonal Shukla () and Springer Nature Abstracting and Indexing ().