Homeostasis or synaptic plasticity?

Yves Frégnac ()
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Yves Frégnac: the Equipe Cognisciences, Institut Alfred Fessard, CNRS

Nature, 1998, vol. 391, issue 6670, 845-846

Abstract: Learning and memory are dependent on synaptic plasticity, through long-lasting changes in synaptic strengths. The two well-characterized forms of plasticity are long-term potentiation (LTP) and long-term depression (LTD). But one group has now discovered a completely different form of plasticity. Whereas LTP and LTD modulate the strength of synapses in a synapse-specific manner, the new form represents a more general regulation of the total synaptic strength of a neuron. And because it is bidirectional, it could have interesting computational properties.

Date: 1998
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DOI: 10.1038/35996

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