SNAREs line up in new environment

Reinhard Jahn () and Phyllis I. Hanson ()
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Reinhard Jahn: Max-Planck-Institut für Biophysikalische Chemie
Phyllis I. Hanson: Washington University School of Medicine

Nature, 1998, vol. 393, issue 6680, 14-15

Abstract: Fusion of intracellular membranes is essential to cellular processes ranging from growth to neuronal communication. But how does it occur? By reconstituting the proteins that are thought to be involved into artificial membranes, one group finds that three so-called SNARE proteins can form ternary complexes and induce interactions between lipid bilayers. These results are consistent with previous theories of how membrane fusion occurs, and they should allow other aspects of the process to be studied.

Date: 1998
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DOI: 10.1038/29871

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