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United we sense ⃛

N. Barkai () and S. Leibler
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N. Barkai: Princeton University
S. Leibler: Princeton University

Nature, 1998, vol. 393, issue 6680, 19-21

Abstract: Some biological systems, such as those involved in chemotaxis, combine high sensitivity with wide dynamic range. For instance the bacterium Escherichia coli can sense chemical attractants over a concentration range of several orders of magnitude, and respond even to small signals in which ligand binds to only a minute fraction of chemotaxis receptors. New theoretical work shows how this may be achieved & the authors put forward the idea that adaptive receptor clustering is the mechanism concerned.

Date: 1998
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DOI: 10.1038/29881

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