The stress of Gulf War syndrome

Robert M. Sapolsky ()
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Robert M. Sapolsky: Stanford University

Nature, 1998, vol. 393, issue 6683, 308-309

Abstract: The symptoms, causes and even existence of Gulf War syndrome have led to much controversy —veterans suspect that chemicals are to blame, whereas the US government maintains that it is a type of post-traumatic stress disorder. But they could both be right. According to a new study, both stress and acetylcholinesterase inhibitors (which were used as a preventative treatment against nerve gas) increase production of acetylcholine in synapses. But eventually this leads to a long-lasting decrease in levels of acetylcholine, decreased neuronal excitability and impaired cognition.

Date: 1998
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DOI: 10.1038/30606

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