Chemokines beyond inflammation

Richard Horuk ()
Additional contact information
Richard Horuk: Berlex Biosciences

Nature, 1998, vol. 393, issue 6685, 524-525

Abstract: The chemokine receptor CXCR4 has been implicated in processes from growth regulation and inflammation to entry of the human immunodeficiency virus. Two groups have now found that mice lacking CXCR4 have a similar phenotype to those that lack its ligand SDF-1 — namely, serious developmental defects in the immune and circulatory systems. But, surprisingly, the mice also show defects in the central nervous system and in the formation of blood vessels within the gastrointestinal tract, indicating that chemokines have much more widespread functions than was initially thought.

Date: 1998
References: Add references at CitEc
Citations:

Downloads: (external link)
https://www.nature.com/articles/31116 Abstract (text/html)
Access to the full text of the articles in this series is restricted.

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:nat:nature:v:393:y:1998:i:6685:d:10.1038_31116

Ordering information: This journal article can be ordered from
https://www.nature.com/

DOI: 10.1038/31116

Access Statistics for this article

Nature is currently edited by Magdalena Skipper

More articles in Nature from Nature
Bibliographic data for series maintained by Sonal Shukla () and Springer Nature Abstracting and Indexing ().