A lesson from secretory granules

Ronald A. Siegel ()
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Ronald A. Siegel: School of Pharmacy S-926, University of California at San Francisco

Nature, 1998, vol. 394, issue 6692, 427-428

Abstract: In the body, secretory granules can store a physiological agent (histamine, for instance) and on stimulation can release it in the right place at the right time. Following that example, a group of researchers has devised an artificial mimic of nature's handiwork using a polymer gel coated with a lipid bilayer. There are endless possibilities for refining the system, but the important hurdle to be overcome is to see if the basic concept worksin vivo.

Date: 1998
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DOI: 10.1038/28756

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