Design and self-assembly of two-dimensional DNA crystals

Erik Winfree (), Furong Liu, Lisa A. Wenzler and Nadrian C. Seeman ()
Additional contact information
Erik Winfree: Computation and Neural Systems, California Institute of Technology
Furong Liu: New York University, New York
Lisa A. Wenzler: New York University, New York
Nadrian C. Seeman: New York University, New York

Nature, 1998, vol. 394, issue 6693, 539-544

Abstract: Abstract Molecular self-assembly presents a ‘bottom-up’ approach to the fabrication of objects specified with nanometre precision. DNA molecular structures and intermolecular interactions are particularly amenable to the design and synthesis of complex molecular objects. We report the design and observation of two-dimensional crystalline forms of DNA that self-assemble from synthetic DNA double-crossover molecules. Intermolecular interactions between the structural units are programmed by the design of ‘sticky ends’ that associate according to Watson–Crick complementarity, enabling us to create specific periodic patterns on the nanometre scale. The patterned crystals have been visualized by atomic force microscopy.

Date: 1998
References: Add references at CitEc
Citations: View citations in EconPapers (11)

Downloads: (external link)
https://www.nature.com/articles/28998 Abstract (text/html)
Access to the full text of the articles in this series is restricted.

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:nat:nature:v:394:y:1998:i:6693:d:10.1038_28998

Ordering information: This journal article can be ordered from
https://www.nature.com/

DOI: 10.1038/28998

Access Statistics for this article

Nature is currently edited by Magdalena Skipper

More articles in Nature from Nature
Bibliographic data for series maintained by Sonal Shukla () and Springer Nature Abstracting and Indexing ().