Does vitamin C have a pro-oxidant effect?

Mark Levine, Rushad C. Daruwala, Jae B. Park, Steven C Rumsey and Yaohui Wang
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Mark Levine: Molecular and Clinical Nutrition Section, Building 10, Room 4D 52, MSC 1372, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health
Rushad C. Daruwala: Molecular and Clinical Nutrition Section, Building 10, Room 4D 52, MSC 1372, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health
Jae B. Park: Molecular and Clinical Nutrition Section, Building 10, Room 4D 52, MSC 1372, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health
Steven C Rumsey: Molecular and Clinical Nutrition Section, Building 10, Room 4D 52, MSC 1372, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health
Yaohui Wang: Molecular and Clinical Nutrition Section, Building 10, Room 4D 52, MSC 1372, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health

Nature, 1998, vol. 395, issue 6699, 231-231

Abstract: Abstract The conclusions of the Scientific Correspondence by Podmore et al.1 are undermined by some unaddressed scientific issues. Podmore et al. gave vitamin C supplements of 500 milligrams to healthy volunteers, and measured levels of vitamin C in plasma and of oxidative DNA adducts in lymphocytes before, during and after supplementation.

Date: 1998
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DOI: 10.1038/26137

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