SNARE the rod, coil the complex

William I. Weis and Richard H. Scheller ()
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William I. Weis: the Department of Structural Biology
Richard H. Scheller: Department of Molecular and Cellular Physiology

Nature, 1998, vol. 395, issue 6700, 328-329

Abstract: Cellular cargo is transported around the cell in small vesicles that are pinched off the donor membrane and then fuse with the target cell. Fusion is mediated by the interaction of proteins -- found on both the vesicle and target membranes -- called SNAREs. The structure of the core fusion complex has now been solved, and changes our ideas about how this process occurs.

Date: 1998
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DOI: 10.1038/26354

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