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Sinking surveillance's flagship

George Klein () and Eva Klein
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George Klein: the Microbiology and Tumor Biology Center, Karolinska Institute
Eva Klein: the Microbiology and Tumor Biology Center, Karolinska Institute

Nature, 1998, vol. 395, issue 6701, 441-443

Abstract: Over 90% of human beings live, for all of their lives, in peaceful equilibrium with Epstein-Barr virus, which infects the immune system's B cells in particular. The proliferation of infected cells is kept under control by T cells, but sometimes this control breaks down and leads to diseases such as X-linked immunoproliferative syndrome. The cause, it turns out, is mutation of a small protein involved in T-cell regulation.

Date: 1998
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DOI: 10.1038/26626

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