Life and death of a signal peptide

Gunnar von Heijne ()
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Gunnar von Heijne: Arrhenius Laboratories, Stockholm University

Nature, 1998, vol. 396, issue 6707, 111-113

Abstract: The signal peptide is a small extension at one end of a newly synthesized protein chain. It directs the transport of that protein across membranes, and is then cleaved off by a signal peptidase. The structure of a bacterial signal peptidase is now reported, and it reveals features that tell us how this unusual enzyme works.

Date: 1998
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DOI: 10.1038/24036

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