Too much sex is bad for males

Amanda Swain () and Robin Lovell-Badge ()
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Amanda Swain: the Section of Gene Function and Regulation, Chester Beatty Laboratories, Institute of Cancer Research
Robin Lovell-Badge: MRC National Institute for Medical Research

Nature, 1998, vol. 396, issue 6707, 115-117

Abstract: In many species, females have two X chromosomes whereas males have only one. To compensate for this difference, genes on the female X chromosomes are switched off. But how does an organism count how many chromosomes it has? A study in the nematode worm has just identified a protein called SEX-1, which represses a gene,xol-1, that is involved in both dosage compensation and sex determination.

Date: 1998
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DOI: 10.1038/24048

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