Support for the lever arm

A. F. Huxley
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A. F. Huxley: Trinity College

Nature, 1998, vol. 396, issue 6709, 317-318

Abstract: Length changes in muscle result from the relative sliding of filaments composed of myosin and actin; the heads of the myosin molecules attach to the actin, exert force and then detach. Several papers provide further evidence for the view that the myosin head acts as a lever arm in this process, rather than tilting as a whole, and for the extent of lever-arm movement.

Date: 1998
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DOI: 10.1038/24503

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