New exchange, new target

Julian Downward ()
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Julian Downward: the Signal Transduction Laboratory, Imperial Cancer Research Fund

Nature, 1998, vol. 396, issue 6710, 416-417

Abstract: The many members of the Ras superfamily of small guanine-nucleotide-binding (G) proteins are thought to be regulated in a broadly similar way. However, a study of the proteins that regulate one member, Rap1, shows that this regulation may be much more varied than previously thought. Not only that, but these studies have unearthed another class of direct target proteins for the second messenger cyclic AMP.

Date: 1998
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DOI: 10.1038/24743

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